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      <link:roleType roleURI="http://www.cvrx.com/role/DisclosureCommitmentsAndContingenciesNarrativeDetails" id="DisclosureCommitmentsAndContingenciesNarrativeDetails">
        <link:definition>41001 - Disclosure - Commitments and Contingencies (Narrative) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
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      <link:roleType roleURI="http://www.cvrx.com/role/DisclosureSegmentGeographicInformationAndRevenueDisaggregationScheduleOfSegmentReportingDetails" id="DisclosureSegmentGeographicInformationAndRevenueDisaggregationScheduleOfSegmentReportingDetails">
        <link:definition>41201 - Disclosure - Segment, Geographic Information and Revenue Disaggregation (Schedule of Segment Reporting) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
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      <link:linkbaseRef xlink:type="simple" xlink:href="tmb-20211231_pre.xml" xlink:role="http://www.xbrl.org/2003/role/presentationLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" />
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      <link:linkbaseRef xlink:type="simple" xlink:href="tmb-20211231_def.xml" xlink:role="http://www.xbrl.org/2003/role/definitionLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" />
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      <link:roleType roleURI="http://www.cvrx.com/role/DisclosureStandardAndCustomAxisDomainDefaults" id="DisclosureStandardAndCustomAxisDomainDefaults">
        <link:definition>99900 - Disclosure - Standard And Custom Axis Domain Defaults</link:definition>
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        <link:usedOn>link:calculationLink</link:usedOn>
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  <xsd:element name="JobsActAccountingElectionPolicyTextBlock" id="cvrx_JobsActAccountingElectionPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
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  <xsd:element name="ClinicalTrialAndOtherProfessionalFees" id="cvrx_ClinicalTrialAndOtherProfessionalFees" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="AccruedPaidTimeOff" id="cvrx_AccruedPaidTimeOff" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ConvertiblePreferredStockWarrantLiabilityMember" id="cvrx_ConvertiblePreferredStockWarrantLiabilityMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="BiosenseWebsterInc.Member" id="cvrx_BiosenseWebsterInc.Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="LoanAndSecurityAgreementMember" id="cvrx_LoanAndSecurityAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="HorizonTechnologyFinanceCorporationMember" id="cvrx_HorizonTechnologyFinanceCorporationMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ThresholdInterestRateOnFirstBusinessDayOfMonth" id="cvrx_ThresholdInterestRateOnFirstBusinessDayOfMonth" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DebtInstrumentFinalPayment" id="cvrx_DebtInstrumentFinalPayment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="DebtInstrumentPercentageOfFinalPaymentOnOriginalPrincipal" id="cvrx_DebtInstrumentPercentageOfFinalPaymentOnOriginalPrincipal" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="LegalFeesAndInvestmentBankFee" id="cvrx_LegalFeesAndInvestmentBankFee" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="IssuanceCostsOfWarrants" id="cvrx_IssuanceCostsOfWarrants" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DebtInstrumentMinimumCashOnDepositRequirement" id="cvrx_DebtInstrumentMinimumCashOnDepositRequirement" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
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  <xsd:element name="Seriesd2RedeemableConvertiblePreferredStockMember" id="cvrx_Seriesd2RedeemableConvertiblePreferredStockMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
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  <xsd:element name="OperationalMilestoneClosingMember" id="cvrx_OperationalMilestoneClosingMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="TemporaryEquityStockIssuedDuringPeriodSharesNewIssues" id="cvrx_TemporaryEquityStockIssuedDuringPeriodSharesNewIssues" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="OtherCountriesMember" id="cvrx_OtherCountriesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="TwoThousandOneStockIncentiveAwardPlanMember" id="cvrx_TwoThousandOneStockIncentiveAwardPlanMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NonOfficerEmployeesMember" id="cvrx_NonOfficerEmployeesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="OfficerEmployeesMember" id="cvrx_OfficerEmployeesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="StockOptionsWithEarlyExerciseOptionMember" id="cvrx_StockOptionsWithEarlyExerciseOptionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="LiabilityRecordedForEarlyExerciseOfStockOptions" id="cvrx_LiabilityRecordedForEarlyExerciseOfStockOptions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="WarrantsToPurchaseSeriesGPreferredSharesMember" id="cvrx_WarrantsToPurchaseSeriesGPreferredSharesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
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  <xsd:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardSharePricePermittedToBePurchasedMinimumPercentagePercentage" id="cvrx_ShareBasedCompensationArrangementByShareBasedPaymentAwardSharePricePermittedToBePurchasedMinimumPercentagePercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="EmployeeStockPurchasePlanMember" id="cvrx_EmployeeStockPurchasePlanMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="TwoThousandTwentyOneEquityPlanMember" id="cvrx_TwoThousandTwentyOneEquityPlanMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
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  <xsd:element name="ConversionOfTemporaryToPermanentEquity" id="cvrx_ConversionOfTemporaryToPermanentEquity" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ConversionOfTemporaryEquitySharesToPermanentEquity" id="cvrx_ConversionOfTemporaryEquitySharesToPermanentEquity" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PaymentsRelatedToReverseStockSplit" id="cvrx_PaymentsRelatedToReverseStockSplit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
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  <xsd:element name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityConversions" id="cvrx_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityConversions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityChangesInFairValue" id="cvrx_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityChangesInFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="EffectiveIncomeTaxRateReconciliationPermanentDifferencesPercent" id="cvrx_EffectiveIncomeTaxRateReconciliationPermanentDifferencesPercent" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="EffectiveIncomeTaxRateReconciliationUncertainTaxPositionPercent" id="cvrx_EffectiveIncomeTaxRateReconciliationUncertainTaxPositionPercent" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DeferredTaxAssetsStartUpCosts" id="cvrx_DeferredTaxAssetsStartUpCosts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="PreferredStockWarrantsConvertedToCommonStockWarrantsAtInitialPublicOffering" id="cvrx_PreferredStockWarrantsConvertedToCommonStockWarrantsAtInitialPublicOffering" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="StockIssuedDuringPeriodSharesWarrantsExercised" id="cvrx_StockIssuedDuringPeriodSharesWarrantsExercised" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PreferredStockWarrantsConvertedToCommonStockWarrantsAtInitialPublicOfferingWeightedAverageExercisePrice" id="cvrx_PreferredStockWarrantsConvertedToCommonStockWarrantsAtInitialPublicOfferingWeightedAverageExercisePrice" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ClassOfWarrantsOrRightsExercisedWeightedAverageExercisePrice" id="cvrx_ClassOfWarrantsOrRightsExercisedWeightedAverageExercisePrice" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DeferredTaxAssetsInternalRevenueCode59EElection" id="cvrx_DeferredTaxAssetsInternalRevenueCode59EElection" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="AccruedLiabilitiesCustomerRebateCurrent" id="cvrx_AccruedLiabilitiesCustomerRebateCurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
</xsd:schema>
